In today's world, most people are eager to find out the secrets to living longer and healthier lives.
If you are looking for ways to extend your life, check out these five podcast episodes. These episodes offer viewpoints from leading experts and explore the realities of long life.
“The Secret to a Long Life” on Radiolab
This Radiolab podcast is about how to make your life feel longer. Sindhu Gnanasambandan, a producer at Radiolab, experiments to find the longest-feeling life possible for her. And the journey leads her to a whole new answer.
She talked to two-time perception researchers, Mark Whitman and David Eagleman, who told her that one way to make time feel longer is to collect memories. They said that our brain measures time by how many memories we have of a certain period. So, if we have a lot of new and exciting experiences, we'll have more memories to look back on, and time will seem to have passed more slowly.
Sindhu Gnanasambandan then decided to spend a week doing only new things to see if she could make it feel like two weeks. She has done things like volunteer at a soup kitchen, learn how to skateboard, and go surfing. She had a lot of fun and had some amazing experiences, but she also got tired and overwhelmed. By the end of the week, she was ready to go back to her normal life.
She concludes that while novelty can make time feel longer, it's not the only way to do it. She said that we can also make time feel longer by paying attention to the little things in life and appreciating them. She quotes her Zen Buddhist priest, Ken, who says that "there is nothing that is not new" if we just pay attention to it.
So, if you want to make your life feel longer, try to have some new experiences, but don't forget to appreciate the everyday things. Savour your morning coffee, take a walk in nature, and spend time with loved ones. These are the things that will make your life feel rich and meaningful, and that's what matters in the end.
“NMN, NR, Resveratrol, Metformin and Other Longevity Molecules” | Lifespan with Dr. David Sinclair
The podcast is about the science of ageing and how to live longer and better. David Sinclair and Matt Laplante discuss different supplements and medicines that have the scientific evidence to be able to give you wellness now as well as long-term health in the future.
They cover a variety of supplements and medicines, including NMN, NR, metformin, berberine, rapamycin, spermidine,resveratrol, fisetin, and quercetin.
NAD+ boosters are a type of supplement that can help increase levels of NAD+ in the body. NAD+ is a coenzyme that is involved in many important cellular processes, including DNA repair and energy production. Some NAD+ boosters that are mentioned in the podcast include NMN, NR, and fisetin.
Metformin is a drug that is commonly used to treat type 2 diabetes. It has also been shown to have some anti-ageing effects.
Berberine is a natural compound that has been shown to have some health benefits, including lowering blood sugar and cholesterol levels.
Rapamycin is a drug that is used to prevent organ rejection after transplantation. It has also been shown to extend lifespans in some animal studies.
Spermidine is a natural compound that is found in foods like wheat germ and soybeans. It has been shown to have some anti-ageing effects in animal studies.
Resveratrol is a compound found in red wine and grapes. It has been shown to have some health benefits, including reducing the risk of heart disease.
Fisetin is a flavonoid found in fruits and vegetables. It has been shown to have some anti-ageing effects in animal studies.
Sinclair and Laplante emphasize that more research is needed to determine whether these supplements and medicines can safely and effectively extend the lifespan of humans. They also caution that people should talk to their doctor before taking any supplements or medicines, as they can interact with other medications or have side effects.
Overall, the podcast provides a helpful overview of some of the latest research on ageing and longevity. However, it is important to remember that more research is needed before any conclusions can be drawn about the safety and efficacy of these supplements and medicines.
The Daily Hacks To Live Longer and Reverse Your Age | Dr. Peter Attia
In this podcast, Dr. Peter Attia mainly focuses on the three key things to do for a longer life.
Exercise: Do more exercise, even if you’re already exercising. Focus on both cardio and strength training. Build muscle and strength with weight training, especially heavy weight training. And aim for high cardio-respiratory fitness.
Diet: Eat 0.8 grams of protein per kilogram of body weight to build and maintain muscle, to avoid chronic insulin elevation, and to have a healthy metabolism.
Mental and emotional Well-being : He suggests practices like meditation and gratitude to manage stress and promote overall well-being.
These are just three of the many things Dr. Attia talks about in his book and podcast. He believes that with hard work and dedication, we can all live a longer and healthier life.
Dr. Rhonda Patrick: Micronutrients for Health and Longevity | Huberman Lab Podcast
This podcast is about a conversation between Andrew Huberman and Dr. Rhonda Patrick on the Huberman Lab Podcast.
Dr. Patrick is a well-known expert in the field of health and longevity and has her own podcast, Found My Fitness. And expertise in cell biology, mitochondrial metabolism, and ageing.
She discussed the importance of micronutrients, which are essential for brain and body health. It then goes on to discuss the different categories of micronutrients that are essential for brain and body health, such as vitamins, minerals, and antioxidants. Dr. Patrick also talks about the importance of getting enough sleep, eating a healthy diet, and exercising regularly, and recommends specific supplements and behavioral protocols.
And it ends with a call to action, encourageing listeners to learn more about Dr. Patrick's work and to sign up for her newsletter. It also mentions that the Huberman Lab Podcast is now partnered with Momentous supplements, which are designed to support brain and body health.
Pioneering Gene Therapy to Combat ageing | Liz Parrish, CEO of Bioviva | Longevity India
This podcast is about the future of gene therapy and how it could be used to combat ageing.
The interview starts by introducing Liz Parrish, the CEO of Bioviva, a company that is developing gene therapies to extend a healthy lifespan. Parrish discusses how gene therapy works and how it could be used to target the hallmarks of ageing, such as telomere shortening and genomic instability.
Telomere shortening refers to the natural process where the protective caps at the ends of chromosomes, called telomeres, become shorter over time. Telomeres act like the plastic tips on shoelaces, preventing chromosomes from sticking together.
Genomic instability refers to a condition where the genetic material within a cell undergoes frequent changes, mutations, or alterations. This instability can lead to abnormalities in the DNA sequence or structure, which may affect how cells function and replicate.
It could be used to treat a variety of diseases, not just ageing. She also talks about the timeline for when these therapies might become available and the challenges that need to be overcome before they can be widely used.
The interviewer Mustafa Inamdar asked her about the science behind gene therapy, the potential benefits of using it to combat ageing, and the challenges that need to be overcome before it can become a mainstream medical treatment.
Parrish provides a clear and concise explanation of the science and the potential benefits of gene therapy. She also acknowledges the challenges that need to be addressed, such as the cost of treatment and the need for more research.
She concludes that she believes that gene therapy has the potential to revolutionize medicine and improve the lives of millions of people. I am excited to see how this technology develops in the future.
This podcast is based on a solid interview with an expert in the field and provides a balanced perspective on the potential benefits and challenges of gene therapy.
1) What are NAD+ boosters?
NAD+ boosters are supplements that can help increase levels of NAD+ in the body. NAD+ is a coenzyme involved in many important cellular processes, including DNA repair and energy production. Some NAD+ boosters include NMN, NR, and fisetin.
2) What are the benefits of anti-ageing supplements?
Anti-aging supplements claim to offer various benefits, including:
Enhanced skin health: Some supplements may promote collagen production, reduce wrinkles, and improve skin elasticity.
Improved cognitive function: Certain supplements aim to support brain health and cognitive abilities.
Enhanced energy levels: Ingredients like antioxidants or vitamins might boost energy and vitality.
Joint health: Supplements may contain compounds believed to support joint flexibility and mobility.
Overall health support: One can consume anti-ageing supplements are NMN and spermidine.
3) What are the tips and tricks to live longer and reverse your age?
Exercise: Do more exercise, even if you’re already exercising. Focus on both cardio and strength training. Build muscle and strength with weight training, especially heavy-weight training, and aim for high cardio-respiratory fitness.
Diet: Consume 0.8 grams of protein per kilogram of body weight daily to support muscle building, maintain optimal metabolic health, and prevent chronic insulin elevation.
Mental and emotional well-being: practices like meditation and gratitude to manage stress and promote overall well-being.
4) Why are micronutrients essential for brain health?
Micronutrients are an essential component of several general cellular functions as well as functions of neurologic activity such as the synthesis of dopamine, serotonin, and myelin formation.
5) What is gene therapy, and how can it combat ageing?
It’s a technique for inserting normal genes into cells in place of missing or defective ones to correct genetic disorders.
Gene therapy holds the potential to combat ageing by targeting specific genes associated with ageing-related processes.
Telomere Extension: Telomeres, the protective caps at the end of chromosomes, shorten with age. Gene therapy could target telomerase, the enzyme responsible for maintaining telomere length, potentially extending cellular lifespan.
Cellular Senescence: Gene therapy might address cellular senescence, where cells cease to divide, by targeting genes involved in regulating this process. Removing or reprogramming senescent cells could potentially improve tissue function and delay aging-related issues.
Oxidative Stress and Inflammation: Genes involved in antioxidant production or inflammation regulation could be targeted to mitigate oxidative stress and chronic inflammation, which contribute to ageing.